In the prefrontal cortex, antipsychotic drugs generated a distinct pattern of gene expression in two regards.
Immunohistochemistry confirmed that the pattern of NAGE protein expression corresponded to the pattern of gene expression.
Each toxic compound induces a specific pattern of gene expression changes.
For example, the pattern of gene expression that occurs in response to YFV-17D in the mice shared significant similarities to that of humans.
Zhang SS, Xu X, Liu MG, Zhao H, Soares MB, Barnstable CJ, Fu XY. 2006) A biphasic pattern of gene expression during mouse retina development.
However, the distribution pattern of gene expression of Wnts in the very early lung development remains unclear.
A particular pattern of gene expression in cells exposed to a potential new drug molecule, for example, might give an indication that the molecule would ultimately be toxic in humans.
Differential Display-PCR analyses of RNA extracted from space-flown cells showed that there was about a 5% change in the pattern of gene expression between cells developing in micro-g compared to those developing on earth.
Dormant spores of the fern Ceratopteris richardii were flown on Shuttle mission STS-93 to evaluate the effects of micro-g on their development and on their pattern of gene expression.
Unexpectedly, patterns of gene expression among normal and moderately deformed embryos were similar, and only severely deformed embryos showed a contrasting pattern of gene expression.
These differences in expression suggest that the visceral yolk sac is more similar to the foetal than adult mouse liver in its pattern of gene expression.
