Sentence examples for pattern of enhancer from inspiring English sources

The candidate enhancers located in orthologous segments of the genome may be derived from a common ancestral sequence and may thus have maintained a similar spatial and/or temporal pattern of enhancer activity.

While the 23 populations sampled were each of different self-declared cultural identity and/or geographic location and are linguistically diverse, there is a strong north-east to south-west cline in the pattern of enhancer diversity with the highest diversity in this data-set being in Sudan.

However, the majority of these were not matched to any known factors, nor linked to any patterns of enhancer activity, so the biological significance of these motifs is hard to interpret.

However, detailed characteristics of this lung enhancer, including the spatial-temporal pattern of the enhancer activity at different developmental or post-developmental stages, are not known.

The expression pattern of this enhancer trap is essentially identical to GH146-GAL4 ([23], also Figure 3C, 3D) except that NP225-GAL4 does not label the anterior paired lateral neuron which innervates the mushroom body lobes [24].

Ludwig et al. showed that the sequence of the even-skipped stripe 2 enhancer was not conserved in two Drosophila species because of transcription factor binding site (TFBS) turnover, but that the activity pattern of the enhancer was restrained to the same stripe and developmental stage in both species [ 11].

We further demonstrate that several nuclear receptors, namely Hr39, Eip75B and Hr46, displaying dynamic expression during metamorphosis, are essential for the temporal pattern of the enhancer-reporter.

Analogy in the expression pattern of CNE-enhancer and one of the many conserved genes solved the puzzle (Additional file 1: Table S1 and Additional file 3: Table S2).

We further demonstrate that several nuclear receptors, displaying dynamic expression during the biological process analyzed, are essential for the temporal pattern of the enhancer-reporter; the fact that some act as activators while others are repressors suggests a subtle balance between these opposite effects, as is the case for the spatial expression during early embryogenesis.

To address this question, CBS automatically produces the map of predicted TFBSs, demanding a certain conservation level in multiple Drosophilids, and includes epigenetic information into the results to favor the selection of regions that show epigenomics patterns characteristic of enhancers.

We observed similar positional patterns of global enhancer signatures across the three different ovarian cancer precursor cell types, and evidence of tissue-specific regulatory signatures compared to non-gynecological cell types.