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In order to eliminate the effect of a random pattern of concordance or fliprates in a series, we modified the consistency-related variables by using a randomized component.
If similar or identical Domains in each major compilation are given a common name, a pattern of concordance emerges.
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In the paragraphs that follow, we discuss patterns of concordance, as well as reasons for the differences.
Where a gene was represented several times on a given platform, an appropriate rule was used to select the "best" gene probe in a manner not biased towards detecting patterns of concordance between datasets (for human lung tumor datasets, the probe with the greatest variation; for MCF-7 datasets, the probe with the greatest difference in either direction by t test between EGFR and control).
These patterns of concordance between dichotomous manual and automated scores were reflected in estimates of association with BCSS (Table 6; Figure 6).
Different histories of dispersal and selection can produce similar patterns of concordance in allelic frequency clines at multiple gene loci, though subtle and discriminating footprints may remain in the genetic architecture of intergrading lineages [ 1].
For each trait, data are compiled on patterns of concordance between differences between Xmat versus Xpat Turner females, differences between 45,X and other Turner females, and differences between males and females in normal populations (Table 1).
Thus, the rational and transparent way to down-weight poorer studies is to consider the impact of this ambiguity as one evaluates alternative interpretations of the data, using the patterns of concordance or lack thereof with other studies as part of the evaluation of the likelihood that the study in question has misled us or informed us.
However, there were a notable number of lesions that were positive with MIBG only and showed a pattern of complete concordance for metastatic disease with the corresponding 111In-pentetreotide images in two of these six subjects.
Such pattern of decreasing concordance was less significant for the relative standard of living question.
A similar pattern of phenotype concordance was seen amongst 12 genes from the tight junction pathway, but a pattern did not emerge from the insulin signalling genes.
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