Indeed, cell transformation is expressed by the alteration of cell morphology, a disorganized pattern of colony growth and the acquisition of anchorage-independent growth which is predictive of their ability to induce tumors when injected into syngenic animals [ 33].
These patterns could complement the traditional cytological assessment of cell morphology, improving the predictive and diagnostic value of the intraduct approach.
Patterning was shown to direct several quantitative measures of cell morphology.
In terms of cell morphology, the length of E. gracilis cells changed periodically with the light dark cycle and photosynthesis, which was analogous to a biological clock life pattern (Lonergan 1983).
However, characteristic features of cells morphology and growth pattern of cultures prompted us to conclude that ultrathin TiO2 layer might also enhance osteodifferentiation of BMSCs.
Blocking JNK signalling by expressing BskDN did not alter the normal pattern of cell proliferation or morphology within the eye disc, however, scrib mutant cells expressing BskDN showed ectopic cell proliferation posterior to the MF and aberrant cell morphology similar to scrib mutants alone.
Otherwise wild-type clones of tissue co-expressing aPKCCAAXDN and BskDN showed a normal pattern of cell proliferation and morphology.
Photodynamic treatments on HeLa cells, using 2.4 or 3.6 J/cm light doses (10 or 15 min irradiation, respectively), resulted in different patterns of cell death morphology: apoptosis or necrosis, respectively, revealed by neutral red (NR) for general morphology and Hoechst-33258 (H-33258) staining for DNA visualization.
In the growth plate, chondrocytes progress through each step of their life cycle in a spatial pattern where cell morphology correlates with the temporal progression of chondrocyte maturation.
There did not appear to be differences in the staining pattern of cell bodies based on the morphology of the neuron (pyramidal vs. non-pyramidal).
