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The pattern of cell death was different in each group.
The pattern of cell death in the otic vesicle was studied by Tdt-mediated dUTP nick-end labeling (TUNEL) of fragmented DNA using the kit Dead-End™ Fluorometric TUNEL System (Promega, Madison, WI) essentially as described by the manufacturer and adapted to whole organ labeling [14], [29].
This is an important issue to resolve because prolonged SE is commonly used to induce a chronic epileptic state, and it is generally assumed that all of the SE-induced changes in animals are excitotoxic in nature [9], and closely related to the pattern of cell death exhibited in human temporal lobe epilepsy [2].
An imbalance between pro-apoptotic and anti-apoptotic factors induces an abnormal pattern of cell death.
The pattern of cell death was similar to liver cancer drug sorafenib (positive control) at all concentrations.
A concentration-dependent cytotoxicity was described [ 7], and an increase in free calcium and reactive oxygen species levels [ 15], a dysfunction of mitochondria and different pattern of cell death were found [ 17].
Similar(45)
The patterns of cell death upon photoactivation of 2 were similar to those observed for 5 (not shown).
Patterns of cell death were observed by flow cytometry.
We did not observe any obvious "border" patterns of cell death, but this may be due to technical limitations.
Recently, two different patterns of cell death were also found on two different cell animal lines after same antimicrotubular drug effects [ 3].
Indeed, the differential patterns of cell death across the retina are indicative of metabolic changes that would be expected following inhibition of Na/K-ATPase activity.
More suggestions(15)
pattern of cell proliferation
pattern of cell motility
pattern of protest death
pattern of cell dispersion
pattern of cell division
pattern of cell growth
pattern of cell mobilization
pattern of cell shape
pattern of cell expansion
pattern of cell wall
pattern of cell anchorage
pattern of cell differentiation
pattern of cell morphology
pattern of cell adhesion
pattern of cell movement
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