Sentence examples for pattern of autoimmune from inspiring English sources

Interestingly, our mAbs showed DNA-hydrolytic activity at an optimum pH of 4 5, which is a typical pattern of autoimmune diseases in which autoantibodies hydrolyze supercoiled plasmid DNA.

We first used Western blotting to explore the Ig Ig interaction patterns of autoimmune pancreatitis patients' IgG4.

Adult-onset autoimmune diabetes emerges as a prevalent form of autoimmune diabetes.

Collectively, these data point to at least two independent associations within the KIAA1109-TENR-IL2-IL21 region, with the pattern of association differing between autoimmune phenotypes (Table 1); one marked by rs17388568 (in the TENR gene) and the other by rs6822844 (which maps between IL-2 and IL-21).

Despite not being associated with Crohn's disease susceptibility itself, FOXO3A variants are thought to affect disease outcome via regulation of IL7 and IL2 signalling pathways, whose expression patterns correlate with clinical course of autoimmune diseases [107].

PRRs also recognize endogenous damage-associated molecular patterns (DAMPs), including alarmins released during microbial invasion, initiation of autoimmune inflammation or tumor growth.

To investigate the pathogenesis of localized autoimmune damage in Sjögren's syndrome (SS) by examining the expression patterns of cytokines, chemokines and chemokine receptors at sites of autoimmune damage.

In this study we analysed PAF-AH plasmatic activity in a large series of unselected patients screened for aPL antibodies in a reference laboratory for the diagnosis of autoimmune diseases, investigating its association with different pattern of aPL positivity.

Nevertheless, in the presence of a pattern suggestive of an autoimmune hepatitis-associated marker, confirmation tests are indicated.

The pattern of genetic association with autoimmune phenotypes varies, suggesting that certain subgroups of autoimmune diseases are likely to share etiological similarities and underlying mechanisms of disease.

The genetic architecture of transcripts differentially expressed in specific stages of autoimmune diabetes offers novel venues towards our understanding of patterns of inheritance potentially affecting the pathological disease mechanisms.