Rosen believes specific protein-cleavage patterns might serve as harbingers of scleroderma, providing a way to diagnose the disease early on.
Thus, it seems clear that both amplitude and temporal differences in the [Ca2+]i signals downstream of different activity patterns might serve as a signal for changing gene transcription.
Although we have not yet parsed the degree to which behavioral changes in humanized animals are due to altered receptor binding affinities, expression levels and/or distribution patterns, this model might serve as a useful investigatory preclinical tool, while providing opportunities for further dissection of the social behavior neural network.
Conceptually, an alteration in the pattern of DNA methylation might serve as an efficient mechanism for genes to adapt functionality in response to a variable environment and also might compensate for the effects of a mal-functional polymorphism.
If this is true, then differing pathophysiology might be mirrored by different patterns of cognitive impairment, which might serve as a more reliable phenotype than categorical diagnoses [ 10].
These and other architectural features are discussed in comparison to the central nervous system of Eumalacostraca, Remipedia, non-malacostracan Crustacea and Hexapoda, and are synthesized into a ground pattern of the malacostracan brain that might serve as a basis for neurophylogenetic discussion of the evolutionary relationship of these taxa.
Under a scenario of colonization with subsequent migration, this pattern could suggest that South Su might serve as a source population that contributes individuals to other sites sampled in Manus Basin.
The objective of this study was to show the spatial distribution patterns of gastric cancer mortality in men and women in Spain, and help to generate new hypotheses which might serve to explain these patterns.
Retinoid regulation of the Notch pathway suggested Notch signaling might serve to link the A-P pattern of retinoid activity and Ascl1 expression in p3 progenitors.
These results show that vSPNs are not necessary for generating rhythmic tail undulations but instead might serve to transform a symmetric motor pattern into an asymmetric motion that underlies a turn.
