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However, following fertilization and during mammalian pre-implantation development, the DNA methylation pattern is dynamic and undergoes reprogramming in the form of a wave of genome-wide de-methylation and re-methylation [ 19– 24], thus putting the embryo at risk of programming errors [ 25].
53 Notably, the Brugada ECG pattern is dynamic and functional; it is more pronounced at night or at rest and may be enhanced by an increase in vagal tone, such as at night or after a big meal, and may become apparent during a febrile illness.
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These results show that the morphological changes of the axon and the UNC-40 localization pattern are dynamic during axon formation.
This pattern was dynamic, such that by late-L4 stage, the presumptive vulE and vulF cells were much brighter compared with the presumptive vulD cells.
However, the direct impacts of CRP on landscape patterns is dynamic across spatial scales and these effects influence the overall perceived impact of CRP to grassland patterns.
In any event, the establishment and maintenance of DNA methylation patterns is dynamic and of critical importance in eukaryotic cells.
As a result, the networks may not operate efficiently, especially when the traffic patterns are dynamic.
Large-scale analyses of DNA methylation patterns have uncovered revealed that DNA methylation patterns are dynamic rather than static and change in a gene-specific fashion during development and in diseased cells.
Investigation of DNA methylation during cortical development has revealed that these patterns are dynamic, indicating methylation alterations in CpG island promoters of genes involved in CNS growth and development [21].
Moreover, DNA methylation patterns are dynamic and vary during development and across the genome.
Although stable and inheritable in somatic cells, global DNA methylation patterns are dynamic during the mammalian life cycle.
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