I particularly appreciated the effort to link genotypes to phenotypes in the form of "target organ toxicity patterns"—in liver, kidney, lung, nervous system, skin, reproductive system -from Chapter 1 onward.
In adult mice, PEITC administration led to prominent induction of UGT1A1 and CYP2B10 in liver and SI tissue, but there was a clear dominance of the induction pattern in liver.
Expression analysis showed that Mmcaspase1 was up-regulated obviously in liver, spleen and kidney, and indicated its positive role in response to Vibrio anguillarum infection, but Mmcaspase3 and Mmcaspase9 showed different expression pattern in liver, spleen and kidney, its showed that different subtypes of caspase having different immune response mechanisms.
Using an 1H NMR spectroscopy approach, we studied the metabolic pattern in liver tissues of Arctic charr (Salvelinus alpinus) fed a commercial diet with unknown composition (ST), a diet with all protein from fish meal (FM) and a diet with most of the protein from zygomycetes biomass (FZ).
Third, liver injury is also unlikely as a mechanism, as AP activity was inversely related to ALT, the opposite of the typical pattern in liver congestion or injury [ 1].
Chan-On, W. et al. Exome sequencing identifies distinct mutational patterns in liver fluke related and non-infection related bile duct canon-infection related
Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high fat-induced insulin-resistant states.
They followed up by using several methods to examine expression patterns in liver and skin tissues for all candidate genes found in those two chromosomal regions.
The binding patterns in liver and spleen suggested macrophage uptake (Figure 3).
Here we report the use of meDIP-seq to determine the genome-wide DNA methylation patterns in liver and muscle tissues of the red jungle fowl and the avian broiler.
