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The expression pattern for tissue transglutaminase (TG2) suggests that it regulates cartilage formation.
The texture-based features Energy and MaxF (COOC) - which describe the spatial distribution pattern for tissue homogeneity - and AVE and MinCDF - which provide gray-level magnitude information on tissue denseness - were the strongest RTA predictors of mutation status within a given ROI.
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Therefore, the presence of specific evolutionary pattern for tissue-specific eQTLs needs future investigation when more tissue-specific eQTLs become available.
Although hidden variables were shared across tissues in both the BNN and DNN, a different set of weights was used following the single hidden layer to predict the splicing pattern for each tissue separately in the BNN (Supplementary Fig. S3).
In accordance with earlier findings, we observed a highly tissue-specific expression pattern for all tissues analyzed.
Hasirci, V. & Kenar, H. Novel surface patterning approaches for tissue engineering and their effect on cell behavior.
When the expression pattern for sporophytic tissue-expressed chlorophyll a/b binding protein family members were examined, none of these transcripts were represented in the pollen-expressed dataset and hence validate our experimental approach.
The results of the qualitative RT-PCR, though not quantitative, were useful for characterizing the pattern of tissue expression.
These results demonstrate that cell-seeded fiber-aligned nanofibrous scaffolds may serve as an instructive micro-pattern for directed tissue growth, reconstituting both the form and function of the native tissue.
Multiple members of a gene family often have different expression patterns, allowing for tissue-specific regulation of the associated activity; for example, PpCESA5 is required only for gametophore development, implying that other PpCESAs produce cellulose in protonemal tissue [ 51].
Epigenomics--along with the Sanger Centre in the U.K., the Max Planck Institute for Molecular Genetics in Berlin, the French National Genotyping Center in Paris, and others--formed the Human Epigenome Consortium (HEC) last December to compile methylation patterns for every tissue.
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