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This is an important point, in that the same enzyme activities that are responsible for the acetylation/deacetylation of nucleosomal histones also acetylate/deacetylate those regulatory proteins that bind to chromatin and probably recognize the complex modification pattern established on nucleosomes.
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A lot of the songs chugged along in waltz time, following a rhythmic pattern established early on by "The Shrew": oom-pah-pah, oom-pah-pah.
It also follows the pattern established early on in its life.
What we say and do would be meaningless if it did not fit into some antecedent structure or pattern established by natural processes, on the one hand, and prior sayings and doings, on the other.
The pattern was established on his Premier League debut for the club, against Arsenal, one that ended with the first red card of his professional career, and has not changed more than two years on as injuries have impacted on his opportunities, pace and form.
Upon replication the same methylation pattern is established on the newly synthesized DNA strand by DNA methyltransferase 1 (DNMT1) and thereby, the methylation pattern is inherited to both daughter cells.
Meanwhile, McNamee's lawyers refused to comment on what their client said in his deposition, following a pattern established by lawyers for the other witnesses.
Upon replication the same methylation pattern is established on the newly synthesized DNA strand by DNA methyltransferase 1 (DNMT1).
Therefore, DNA-methylation provides an ideal mechanism as the methylation pattern is established on the newly synthesized DNA strand by DNA methyltransferase 1 (DNMT1) [ 43, 44].
The maintenance of H3.3 in sperm might explain how the domain pattern is established on paternal chromatin upon fertilization, even though cenH3 is not maintained in mature sperm (Gassmann et al., 2012).
Thus was an under-the-radar pattern established.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com