(a) Gene expression pattern of each gene in the small intestine of W/W V mice.
The algorithm reports a P-value for the matching pattern of each gene, and a global false discovery rate can also be computed.
Cells in which the pertinent gene was active turned purple, and each slice was then photographed.The atlas itself was constructed by reassembling the photographs into three-dimensional images of the activity pattern of each gene.
However, the expression pattern of each gene differed.
The expression pattern of each gene is standardized between −1 and 1. Known network motifs are extracted from the combined molecular interaction network.
After averaging over the corresponding time points in both experimental runs, a Fourier score was calculated for the temporal expression pattern of each gene.
STEM selects a set of model profiles independent of the data, and the algorithm decides which model profile best fits the expression pattern for each gene.
In moricin family, the expression pattern of each gene induced by E. coli was similar to that of the fungus P. pastoris (Fig. 4B).
Accordingly, the evolutionary pattern of each gene may be restricted by its "niche", the neighbor genes which directly interact with the gene and the conditions where the gene expresses.
To analyze the quantitative expression pattern of each gene by RT-PCR, the cDNA strand was synthesized from 2 µg of total RNA using oligo (dT) primers and Moloney murine leukemia virus (MMLV) reverse transcriptase (SuperBio Co., Korea).
