We also verified that variation in levels of purifying selection in genes of different LS categories is not due to the variation in the level of gene expression, although A*/S* is strongly influenced by the expression pattern and breadth (Osada 2007).
Non coding gene sequences, showed different patterns between expression breadth and level: introns and UTRs were positively correlated to expression breadth and negatively or not even associated to expression level.
Broadly distributed taxa display heterogeneous patterns over a breadth of environmental and ecological conditions [ 11, 12].
To compare patterns of similarity, breadth, and overlap of the fundamental and realized ecological niches of each taxon, we adopted two approaches.
The fact that the inferred expression patterns exhibit greater breadth of expression than the starting tissues is in line with the notion that genes tend to be expressed in complex spatial and temporal patterns.
For expression level we used the median expression across tissues; for the expression breadth or pattern, the variability between tissues; and for noise, the variability between biological replicates.
To determine the importance of gene expression levels in preserving neo-Y genes, we explored if other factors were contributing to this pattern, including gene function, breadth of expression, or protein connectivity.
Deep, rich, largely tonal harmonies evoke the ocean's breadth; flurrying patterns in the upper registers suggest a rapidly changing sky.
"What do girls learn about who they should be," she asks, "from Lego kits with beauty parlors or the flood of 'girl friendly' science kits that run the gamut from 'beauty spa lab' to 'perfume factory'?" I think Ms. Orenstein is right to ask that question — and to remind us that our buying choices, as parents, can either reinforce stereotypically gendered play patterns or promote greater breadth.
For instance, life science aims at extracting common patterns from the full breadth of natural diversity.
