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Such biological samples are not readily available, since patients only present for treatment when their symptoms appear.
Some mainly polygenetic disorders can also be studied by using platelets although the patients only present with a subtle subclinical platelet phenotype.
Although patients only present with one or two node areas that are clinically affected, the staging study showed dissemination affecting the spleen, liver or bone marrow in 40%, 50% and over 60% of patients, respectively.
The blood film will only be read immediately if the patient is symptomatic (i.e. has a fever or a history of fever in the preceding 24 h); this mirrors the real world scenario of passive case detection when patients only present to a clinic if they are sick.
Similar(56)
ML patients only presented mucosal lesions, but seven patients reported history of previous cutaneous lesions.
The other 29 patients only presented with pathological evidence of renal TMA.
This may well be because, in their series, patients only presented once they had become symptomatic and the disease had become extensive.
Treatment regimen is being well tolerated and the patient only presents minor skin-related toxicity (maximum grade 2).
A motor deficit was defined as any impairment of motor performance even if the patient only presented with deteriorated fine motor skills of the small hand muscles.
Genomic sequencing revealed compound heterozygous mutations in the mitochondrial transfer ribonucleic acid modifying factor (TRMU) in a single patient only, presenting with early onset, reversible liver disease.
At 5 months, the patient only presented occasional discomfort in the popliteal region, mild atrophy of the quadriceps and minimum non inflammatory effusion that was drained and sent to microbiological study.
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CEO of Professional Science Editing for Scientists @ prosciediting.com