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b, Expression profiles of the GBM specimens from patients at study entry, according to RNA-seq analysis (Methods).
Radionuclide splenic uptake was absent in 47% of patients at study completion, compared with predicted functional asplenia in 80% of the patients.
PARTICIPANTS All ICU patients at study hospitals during the study period.
The mean statin dose was higher in group medical clinic patients at study midpoint and end.
Informed consent was obtained from the patients at study entry.
The initial sample size of 180 patients at study entry was subsequently reduced to 147 patients at 48 hours and to 100 patients after one week due to either ICU death (16 patients at 48 h, 22 patients at day-7), ICU discharge alive (10 patients at 48 h, 26 patients at day-7) and/or non-available samples (7 patients at 48 h, 1 patients at day-7).
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Patients in J-FOCUS presented with multiple symptoms: the mean number of upper GI symptoms reported by each patient at study entry was six.
The assessment of each patient at study entry and at each annual review included a comprehensive questionnaire and physical examination (8).
Rhythm- and rate-control strategies were applied to 55% and 45% of patients, respectively, at study inclusion.
Plasma samples were obtained on admission from SAP patients and at study entry from healthy individuals.
Table 1 shows the patients' characteristics at study entry.
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