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The bronchial tissue samples were biopsied from patients appointed to fiber optic bronchoscopy for different clinical indications.
The patients appointed to the fixed dose group were given 3 doses of AS+SMP f orally as a fixed combination (one single tablet every 12 hours (a total treatment lasted 24 hours).
We analyzed a group of 115 patients appointed to PET-CT due to increased serum S100B value (33 pts) or clinical signs of disease progression encountered during regular follow-up (82 pts).
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Legal agency is mediated by the courts but at present very few patients have appointed a legal representative.
Patients were appointed to the German Heart Center Munich one day prior to the scheduled intervention and stayed hospitalized for three to four days provided that the intervention proceeded without complications.
Patients are appointed a responsible doctor for the outpatient trajectory.
In both departments, forms were completed when patients were appointed to follow-up examinations.
Because this study is a pharmacological intervention study recruiting (vulnerable) older patients, we appointed a Data Safety Monitoring Board (DSMB).
After recruitment, patients were appointed monthly to the ART clinics of the respective hospitals to take their medication (anti-retroviral and ant-TB drugs).
Only 21 patients were appointed due to a partial booking system where parents had to phone in to book their appointment once notified by the hospital by letter.
The main limitation of our study is that patients were appointed to PET-CT based on the increased S100B or clinical suspicion of disease progression which represents a selection bias influencing NPV and specificity of S100B.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com