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Recovery according to the patient will be used as an external criterion.
Plots of drug doses over time for each patient will be used to visually identify trends and outliers.
A patient example of a knee OA pain patient will be used throughout the intervention as a basis for discussion and practice in problem solving.
The monthly PDC of each patient will be used to describe trajectories or patterns of adherence (trajectory models or latent class growth analysis models) for each drug.
All exacerbations from each patient will be used as the dependent outcome to evaluate the effect of physical therapy at the end of the intervention (12 months) and follow-up (24 months).
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A new format for patients will be used to deliver both treatment approaches.
Evaluations of patients will be used to determine outcome measures for change and variability.
To evaluate the accuracy, the geometric GH-JRC determined on the post-operative CT-scan images of the patients will be used as the reference of comparison.
For the primary analysis, only evaluable patients will be used.
A computer using block randomisation of 10 patients will be used to create a randomization schedule.
The newer XL probe, specifically designed for obese patients, will be used for FibroScan [ 86].
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