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Having emerged from previous patient stages and achieving a new level of success, will actually make the company more resilient through the next patient stage.
While such great variability have been attributed by those presented models to tumors variability in growth rate (tD) propensity for metastasis, or in other words, to the specific patient stages and consequently their corresponding grades.
Figure 2 shows the distribution of patient stages for the whole population.
According to the pTNM classification, the patient stages were as follows; 1 (stage I), 9 (stage II) and 4 (stage III).
Clinical and pathological staging was performed using the TNM92 system, and patient stages were either pT2N0M0 or pT3N0M0 (casuistic is summarised in Table 1).
We used patient stages assigned by the event-based model to discriminate cognitively normal subjects from those with Alzheimer's disease, and predict conversion from mild cognitive impairment to Alzheimer's disease and cognitively normal to mild cognitive impairment.
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Below are the keys to surviving the patient stage.
Avoid fundraising at all costs while in the patient stage.
First and most obvious, the shorter each patient stage the better.
The question for founders and their boards is how to get through the inevitable patient stage together.
I've seen companies stay in the patient stage for a few years and others that cannot survive through this stage for more than a few months.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com