Sentence examples for pathways without the from inspiring English sources

Additive Manufacturing (AM) is a novel process that promises an increased efficiency in material use, while allowing the production of advanced topologies and the seamless integration of inner cavities and pathways without the use of complex tooling.

A sensitivity analysis of the chemical pathways suggests that the n-propylbenzene forms PAH via direct pathways without the need to break the aromatic ring unlike n-dodecane which breaks down to C1C4 species; this results in PAH forming earlier and in greater magnitude.

By inheriting the advantages of the bootstrap method and graph theory, the BootGraph method provides a computationally efficient and flexible probabilistic tractography setup to compute connection probability maps and virtual fiber pathways without the drawbacks of streamline tractography algorithms or the assumption of a noise distribution.

More generally, these results could set the basis for a designer neurotrophin for those applications where targeting selectively TrkA pathways, without the confounding actions associated to p75NTR, would be advantageous.

In addition to its classic nuclear receptor activity, some of progesterone's effects are "non-genomic" and can be explained by extranuclear signaling that involves rapid activation of Src/MAPK (mitogen-activated protein kinases), phosphoinositide 3-kinases/Akt and JaK2/Stat3 signaling pathways without the transcriptional activities of the receptors [77], [78].

Mosaic Eucalyptus trees provide a unique opportunity to investigate specific biosynthetic pathways without the usual challenge of variation between individuals.

Indeed, the success of a drug discovery process depends on multiple aspects, not least on the fulfillment of requirements regarding selectivity and toxicity: for metabolic diseases the modulation of the key pathways without affecting the other vital functions can be instrumental for rescuing from the pathology.

In other words, the pathogenic genes are more possibly involved in same pathways in which genes work together, and the pathogenesis is possibly regulated by these pathways without affecting the normal processes considering the modularity and robustness of the biological system.

This approach avoids artificial grouping and reduces the number of pathways without reducing the numbers of proteins and interactions.

This strategy is aimed at inhibiting the formation of C5a and C5b-9 via both the classical and alternative pathways, without affecting the generation of C3b, a C3 opsonic product that is critical for antibacterial defences [88].

Remarkably, the optimality assumption is sufficient to predict (i) the substrate preference, and (ii) the use of fermentative or respiratory pathways, without representing the complex regulative machinery that cells have evolved in order to govern these processes.