Sentence examples for pathways with strong from inspiring English sources

We identify several significant pathways with strong biological connections.

It appears that ROS generation, signaling, and scavenging are part of a delicate network of interacting pathways with strong impact on aging and development.

We gave more weight to pathways with strong trends in expression patterns (i.e., most genes similarly regulated), alterations in related steps, altered receptors, or groups of genes with broad-reaching effects and to pathways altered by multiple chemicals.

It was used to show that the maximum channeling degree in branched pathways depends on the strength of the side reactions, suggesting that proximity channeling in a physical tunnel is more suitable for a pathway with strong side reactions.

Drosophila Groucho and its human Transducin-like-Enhancer of Split orthologs (TLEs) function as transcription co-repressors within the context of Wnt signaling, a pathway with strong links to cancer.

In agreement with its biological function, the lack of KMT2D protein activity or of its ability to form a multiprotein complex might alter its role in histone methylation pathway with strong influences on global change in gene expression in many of the body's organs and tissues, resulting in some of the abnormalities of postnatal development of KS.

The 756 genes-based molecular signature was subjected to a detailed analysis, revealing the presence of several NF-κB target genes and upstream activators of the NF-κB signalling pathway, with strong expression in IBC as compared to non-IBC (Van Laere et al, 2005).

These can be grouped into three main functional categories: 1) metabolic pathways such as Glycerophospholipid metabolism or Aminosugar metabolism, 2) pathways with a strong signalling component such as Parkinson's disease, Phosphatidylinositol signalling and Prostate cancer and 3) cell communication pathways such as Cell communication and Focal adhesion.

The six pathways (40%) unique to the CSCH group could be grouped into two main functional categories: (1) biosynthetic pathways, and (2) pathways with a strong signalling component such as ErbB- and Wnt signalling as well as tight junction.

Furthermore, the stoichiometric complexity of metabolic pathway, along with strong nonlinear behaviour of the regulatory kinetic models, directs a highly rugged contour in the whole optimization problem.

A pathway was deleted from CattleCyc after comprehensive literature search if 1) either the input or the output of the pathway is not present in any mammal (e.g. peptidoglycan biosynthesis), or 2) neither enzyme activity was reported nor homologs were identified in any mammal, and an alternative pathway exists with strong biochemical evidence (e.g. putrescien degradation I).