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The MetaCyc tool [25] (http://metacyc.org/) was used to identify P. sojae gene models from several metabolic pathways with multiple examples of novel MF proteins.
The complex nature of protein signaling networks, such as apoptotic pathways, with multiple variables acting at the same time, can be analyzed using a systems level probabilistic approach.
Subsequently, the global p-value (PG) was calculated from PNDE and PPERT for the selection of significant pathways with multiple adjustments (PGFDR) [ 13].
However, due to equilibria between open- and closed-ring forms, the AlkB repair reactions of exocyclic dG lesions are complex, involving overlapping pathways with multiple convergence points.
Deeper analysis of the specific pathways showed, pathways with multiple regulated features including sterol/steroid biosynthesis with 10 genes down-regulated in fish fed FO (Fig. 5).
Functional redundancy is a characteristic of DNA repair pathways with multiple structure-specific enzymes sharing common substrates and/or activities that are controlled by regulatory factors.
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Because some of these pathways intersect with multiple pathways, we speculate that these pathways are temporally and spatially multi-tasking.
Spontaneous preterm birth (SPTB) is a complex condition that is likely a final common pathway with multiple possible causes.
In addition to engineering, this work better defines the macrocyclization mechanism, provides the first biochemical demonstration of Ser/Thr posttranslational prenylation, and is the first example of reconstitution of a native, multistep RiPP pathway with multiple enzymes in one pot.
We established that DAG stimulates endocytosis of Tf in Leishmania major, and we evaluated possible effector enzymes in the pathway with multiple approaches.
This might be due to the cross-talk of PI3K/AKT/mTOR pathway with multiple other signalling pathways leading to multiple sites of regulation.
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