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Among both pathways, which play an important role in the inflammatory response, 4 members of the co-expressed cluster were found (socs3, cxcl1, Il-13ra1, cish).
One suite of the molecular mechanisms that results in the removal of highly compromised symbionts from stressed host tissues involves regulation of cell death pathways which play active roles in maintaining tissue homeostasis and immune responses [2], [6], [10], [11].
Indeed, besides activating striatal dopamine signaling, cocaine also activates brain stress pathways, such as the extra-hypothalamic corticotropin-releasing factor pathways which play a critical role in fear and anxiety [55].
It can potentially be applied to explore novel pathways which play important roles in life threatening disease like cancer.
We focused on the PI3K/AKT and p53 pathways which play important roles in ovarian cancer [ 40- 43].
Consequently, LRP1 is suggested to be involved in two major cell processes: endocytosis and modulation of signaling pathways, which play diverse biological roles in cancer cells.
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It is possible that deregulations in dopamine pathways, which plays an important role especially in etiopathogenesis of migraine, affect the sexual functions negatively [24, 30, 31].
NFκB is one of the cross-talk points of multiple signal transduction pathways, which plays a key role in inflammatory responses.
Synthetically, primary tumor harbored more alterations located in Wnt, cell cycle, JAK-STAT pathways, which plays an important role in encoding protein molecular emphasizing the cell proliferation, apoptosis and inflammation, as well as focal adhesion pathway.
They were important components of the two major pigment synthesis pathways in teleost fish: the melanin and the pteridine pathways, which played important roles in the generation of black and yellow pigments, respectively.
YAP and TAZ are transcription coactivators and effectors of the Hippo pathway, which play a key role in organ size control.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com