Sentence examples for pathways which modulate from inspiring English sources
Moreover, in response to metabolic and genetic stress mitochondria and nucleus engage in bidirectional signaling pathways, which modulate cell function [4, 34, 35].
Thus, we evidenced that FAK promotes SK-Hep1 cancer cell migration and invasion in concert with the activation of the MAPK and PI3K/Akt signaling pathways, which modulate the MMP expression.
In the face of large fluctuations of intracellular calcium ([Ca(2+)](i)) that occur with contractile activity, myocytes are able to sense and respond to changes in workload and patterns of activation through calcium signaling pathways which modulate gene expression and cellular metabolism.
In this study, we set to explore the potential signaling pathways which modulate the expression of the exsCEBA operon.
An important future challenge is the determination of the signaling pathways which modulate the activity of miRNA processing accessory factors such as KSRP and hnRNPs.
The interaction between integrins and their ligands mediates cell adhesion to either extracellular matrices or biomaterials, stimulating intercellular signaling pathways which modulate cell function.
Stress exerts its effects on immune effectors through two primary pathways: the sympathetic adrenal medullary pathway, and the hypothalamic pituitary adrenal pathway which modulate adaptive immunity and lymphocyte migration.
We hypothesized that JP45 and CASQ1 form a signalling pathway which modulates Cav1.1 channel activity.
However, the work by Quesada and colleagues (Quesada et al., 2008), using female rats, demonstrated that DA cell survival was dependent on estradiol acting via the IGF-1 system operating through the phosphatidylinositol 3-kinase (PI3K /Akt (PKB) pathway, which modulates expression of anti-apoptoic (Bcl-2) and apoptotic (Bad, Bax) proteins to promote cell survival.
The contribution of key embryonic regulators such as SOX2 points to the conservation of critical developmental pathways in cancer cells, which modulate their response to the disruption of oncogenic signals.
Emerging clinical evidence also appears to tentatively support certain nutrients and plant-based interventions with known active constituents which modulate these pathways: N-acetlycysteine, myo-inositol, glycine, and milk thistle (Silybum marianum).
