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In all cases, the xylose consuming pathways were optimized by overexpressing the pentose phosphate pathway (de Las Heras et al. 2016; Sandström et al. 2015).
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The raw-material and bio-fuel transportation pathways are optimized using a geographical information system (GIS).
How can synergies between climate and development pathways be optimized?
Natural biochemical pathways are optimized through evolution for their ability to adapt and not necessarily for a particular function, as is typically required for industrial applications.
In our method, these parameters were optimized so that pathways that are fully annotated in the reference database, for instance KEGG, are ranked first with respect to predicted pathways (see details in Methods).
All parameters in the scoring scheme (, and ) were optimized to maximize the agreement between protein protein co-occurrence scores and KEGG pathways (30).
They were optimized for ramming.
Fermentation conditions were optimized.
Operators were optimized automatically.
This fastens the design of metabolic circuits using a combinatorial design approach, where given pathways could be optimized for maximal bioproduction, while being nontoxic for the chassis.
The GR signalling pathway has been optimized for a prompt and timely response to fluctuations in hormone levels, indicating that biologically accurate regulation of gene targets by GR requires an ultradian mode of hormone stimulation.
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