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As a result, 33 unique pathways were obtained from the shared pathways by GWAS datasets or PBA tools.
Among these efforts, some modifications to metabolic pathways were obtained good effect on increasing butanol/acetone ratio.
For low interfacial tensions, improved predictions of migration pathways were obtained through grid refinement and incorporation of small-scale packing variability.
Minimum-energy pathways were obtained for both the forward and reverse reactions, and the enthalpy difference between the transition and reactant states found to be 32 kcal/mol.
Gene sets from GO, BBID (Biological Biochemical Image Database), Biocarta, and Kegg pathways were obtained from DAVID Bioinformatics Resource (http://david.abcc.ncifcrf.gov).abcc.ncifcrf.gov
Sulfur utilization biosynthetic pathways were obtained from AraCyc v3.4 (http://www.arabidopsis.org/biocyc/) and modified to better organize the pathways based on metabolites of importance for glucosinolate synthesis (Table S8).
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Finally the gene regulatory pathways are obtained through optimization of an objective function with respect to these weighting coefficients.
A complete set of 522 cellular pathways was obtained from the Molecular Signatures Database (MSigDB) created by the Broad Institute at the Massachusetts Institute of Technology [53].
All these real life pathways are obtained from the KEGG database [ 14].
Finally, an optimal feature set including 1061 GO terms and 8 KEGG pathways was obtained.
The human pathway collection containing 262 pathways was obtained from WikiPathways (http://www.wikipathways.org, see Additional file 2).
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