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Proteins involved with the FDG uptake as well as the MAPK and AKT pathways were measured by western blot (Figure 5).
DNA Damage Response (DDR) and apoptosis pathways were measured using p-Chk2 and cleaved PARP after in vitro exposure of AML samples to etoposide, Ara-C/daunorubicin or staurosporine.
Phosphorylated forms of 17 proteins that are components of signaling pathways were measured.
Core nodes (i.e., core genes) among multiple pathways were measured by implementing KEGGgraph R package (version 2.10) [ 33].
The functional activities of the three complement pathways were measured in sera obtained from the HD patients and healthy controls.
In human LN229 and drug-resistant T98G glioblastoma cell cultures, cell death and signal pathways were measured using immunocytochemistry and Western blotting.
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The significance of the association between the data set and the canonical pathways was measured in 2 ways: 1) A ratio of the number of genes from the data set that map to the pathway divided by the total number of genes that map to the canonical pathway is displayed.
The FDR of the pathways was measured by applying the Benjamini algorithm in SPIA.
The activation of PI3K/Akt signaling pathways was measured by Akt phosphorylation on Ser473.
Related gene expression involved in three pathways was measured for anti-diabetic mechanism identification.
The significance of the association between the data set and the canonical pathways was measured as described previously [ 27].
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