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Using this method, 17 shared pathways and 5 specific pathways were found to be significantly differentially expressed following infection with the two iridoviruses, among which 11 pathways were additionally identified based on the proposed method of multiple reference species selection.
Several KEGG pathways were additionally up-regulated by ferulic acid, including ATP-binding cassette (ABC) transporters and sulfur metabolism (Table 2).
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Perturbation of signalling pathways is additionally determined by GSTM1 genotype.
A set of 17 selected genes from several differentially expressed pathways was additionally analyzed with quantitative real-time PCR and confirmed to be suitable for a reliable classification of infected plants and for the characterization of susceptibility features in the field conditions.
To determine the rate-limiting gene on plasmid ME, each constituent gene of the MEP pathway was additionally overexpressed on the plasmid AO.
For epithelial cells, the ectopic expression of telomerase was not sufficient for their immortalization; inactivation of the Rb/p16 pathway was additionally required [12].
The Notch signaling pathway is additionally regulated by increased expression of its inhibitor, Numb that can antagonize the activity of NICD preventing its nuclear translocation [28].
3 The PI(3 K/AKT pathway is additionally emerging as a key player in ccRCC tumorigenesis.
The pathways identified were additionally successfully applied to discriminate subgroups depending on recurrence risk within the public HCC datasets.
Two full length cDNA clones for the first enzyme of the MVA pathway (HMGS) were additionally established from the charophycean green alga Chara vulgaris by library screening.
Other diverse pathways, such as lysosome, endocytosis, and hemostasis, were additionally associated with recurrence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com