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This allows to systematically identify and incorporate many intensification pathways using a general block-based superstructure.
Further, most heterologous expression efforts to date typically rely on overexpression of exogenous pathways using a handful of poorly characterized promoters.
To understand the differences between glucose and engineered xylose metabolic networks, we performed a flux balance analysis (FBA) and calculated extreme pathways using a stoichiometric model that describes the biochemistry of yeast cell growth.
Tup1 and its recruiting proteins integrate the signals from these pathways using a number of mechanisms.
The predicted TFs were then assigned to signaling pathways using a public database to determine the contribution of specific biological pathways to gene transcription.
Accordingly, we further investigated differences in amplitude of Ras activity in ErbB signaling pathways using a detailed upstream model modified from Kholodenko's [26].
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Lightweight Kvik Pathways uses a powerful backend provided by the Kvik framework to perform statistical analyses.
Both pathways use a complex formed by IκB kinase proteins, however, in slightly different compositions [ 2, 7].
Modification of the Cdk4 pathway using a natural plant-derived compound such as silibinin may be a useful chemopreventive strategy for colorectal carcinomas.
To address this gap, we previously developed two N-of-1-pathways methods, Wilcoxon and Mahalanobis distance, to detect unidirectionally responsive transcripts within a pathway using a pair of samples from a single subject.
The report's authors asked 1,800 respondents to complete Decc's My2050 tool, which allows each user to create their own energy "pathway" using a combination of 14 different energy options to reduce UK emissions by 80% by 2050.
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