Sentence examples for pathways to survive from inspiring English sources

Malignant cells must circumvent endogenous cell death pathways to survive and develop into cancers.

In Apaf1 deficient cells, Ferraro et al. have demonstrated that such cells can turn-on readjustments of metabolic pathways to survive apoptotic stimulus while the depolarized state of mitochondria is reverted (Ferraro et al., 2008).

New discoveries have revealed important parallels between wound healing and metastasis, and cancer cells may rely on these pathways to survive and metastasize.

Cancer cells alternate between glycolysis and protein synthesis pathways to survive and proliferate during stress associated with tumor growth and prolonged metabolic and anaerobic stress [ 2].

Since cancer cells are under stress and highly dependent on aberrations of apoptosis signalling pathways to survive, selective killing of tumour cells might be achievable with apoptosis-promoting drugs.

These results suggest an enhanced regulatory ability for the bovis group, where strains can activate/deactivate multiple metabolic pathways to survive in resource poor environments such as the colon.

In its life cycle, T. congolense is incapable of synthesizing purine nucleotides via a de novo pathway, and thus relies on a salvage pathway to survive.

In virtue of their pluripotency, these cells represent a salvage pathway to survive genotoxic insults [ 71].

Fungal pathogens have adopted the calcineurin pathway to survive and effectively propagate within the host (reviewed in [ 37, 51]).

Overall these data suggest that 22Rv1 cells require an active Raf/MEK/ERK pathway to survive and that interrupting this pathway by sorafenib leads to the activation of Bad and consequent cell killing.

One of the main hypoxia-induced cellular responses is autophagy, a lysosomal-mediated degradation pathway used to survive starvation and stress.