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This indicates that TOR and autophagy act via the same signaling pathways to affect lifespan.
These results indicate that LHX8 indirectly interacts with the members of the PI3K-AKT-mTORC1 pathways to affect PFA.
By itself, M protein can induce death in mammalian cells [41], [44] and can also modulate cellular signaling pathways to affect the immune response [49].
Interestingly, genetic experiments in worms have revealed distinct temporal requirements for the longevity pathways to affect lifespan (Dillin et al., 2002).
These previous studies have demonstrated that miRNAs can regulate key genes in disease resistance pathways to affect viral infections [ 13, 17, 18, 45, 46].
We observed that regulation of the actin cytoskeleton could be one of the most important pathways to affect TNBC cell migration.
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Although yeast cells lack Src family members, it is possible that E4orf4 may also utilize a backup mechanism which allows it to interact directly with components of the secretory pathway to affect protein trafficking, thus further transducing its toxic signal.
In addition, a recent report revealed that hTERT facilitates Wnt signaling by binding BRG1, a histone remodeling protein that signals through the β-catenin pathway, to affect proliferation and cell survival of progenitor cells [28].
Our genetic analysis indicated that BB polyphenols may act through a CaMKII signaling pathway to affect C. elegans lifespan.
As mekk-3 works independently of the IIS and TGF-beta-like pathway to affect lifespan, we investigated its role in other longevity pathways.
They found that a neglectful maternal parenting style interacts with the verbal information pathway to affect the child's physiological response to verbal threat information.
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CEO of Professional Science Editing for Scientists @ prosciediting.com