Sentence examples for pathways to activate from inspiring English sources
High osmolarity responses include a rapid and transient accumulation of intracellular cAMP and of intracellular cGMP that functions, in parallel to Ca2+-based pathways, to activate the stress-activated transcription factor STATc [ 19, 21, 26, 27].
We further determined that BMP4 mediates RPE senescence via activation of Smad and p38 pathways to activate p53, and increase expression of p21WAF1/ cip1, and to decrease phospho-Rb.
The PR also interacts with cytoplasmic signaling pathways to activate c-Src family members [ 26], and PR interactions with the mitogen-activated protein kinase pathway are also described.
Viruses, bacteria, parasites and injury initiate distinct signal-transduction pathways to activate NF-κB.
These new agents will also be useful for targeting distinct signaling pathways, to activate selectively mechanisms for apoptosis in cancer cells but devoid of undesirable side effects.
Exposing of anestrous goats to testosterone-treated bucks, irrespective of mating load, was able to successfully invoke neurophysiological pathways to activate ovarian function and to promote a uterine milieu prone to the establishment of pregnancy during the anoestrus season.
It suggested that activated Src might trigger PI3K pathway to activate Akt, which regulated multiple cellular proteins in cell proliferation, apoptosis, metastasis and angiogenesis.
Mechanistically, BMP2 functions downstream of Lrp5/6 pathway to activate a conserved regulatory element upstream of Sp7 via recruitment of Smad1 and Grhl3.
M2 polarization is driven by products of mast cells, TH2 cells, and basophils including IL-4 that signals through the Jak-STAT signaling pathway to activate the latent transcription factor STAT6 (Chawla et al., 2011).
Furthermore, Foxc1 and Foxc2 cooperate with the VEGF signaling pathway to activate the Dll4 and Hey2 promoters.
Data suggest that LGP2 may be acting downstream of the intracellular RNA polymerase III pathway to activate anti-microbial signaling.
