Sentence examples for pathways to act from inspiring English sources

In any case, we cannot rule out a potential neuralizing effect of Gem to explain our results, neither can we eliminate the possibility that the neuralizing action of Gem suggested by previous work results from a failure of non-neuronal fate determinant pathways to act after S-phase arrest.

This feedback loop would maintain cellular protein synthetic capacity, and also allows for external growth stimulatory pathways to act through Myc to control the protein synthetic activity of cells [see also (Grandori et al. 1996; Zaffran et al. 1998; Greasley et al. 2000; Xie and Varshavsky 2001; Grewal et al. 2005; Lundgren et al. 2005)].

The United States should "confront Egyptian leaders with a set of stark choices that would give them a pathway to act as responsible national leaders rather than as religiously inspired ideologues," the report said.

We first examined if bar-1 function was required cell-autonomously for D-type axon guidance, a necessary condition for the canonical pathway to act downstream of Wnt/Fz in this process.

We have also found that arginyl-tRNA protein transferase (Ate1), a key component of the N-end rule pathway in the ubiquitin (Ub -proteasome system, binds to heme and allows the N-end rUb -proteasome act asystemnsor of heme and redox state (Hu et al., 2005, 2008; Kwon et al., 2002; Varshavsky, 2012).

Both pathways appear to act independently and equally to mediate the effects of Ox-AT.

In T cells, as in macrophages, Twist1-mediated repression of NF-κB-activated pathways seems to act through binding to E-boxes in regulatory regions of NF-κB target genes.

It is also possible that the increased chondrocyte S100a8 and S100a9 mRNA in early MMD-induced OA was not translated into protein, through micro-RNA silencing pathways predicted to act on the mRNA of both genes [ 34, 35].

The GDNF/Ret, FGF and Wnt signaling pathways are necessary for normal branching [4], [9], [10] while the BMP pathway appears to act as a branching inhibitor [11].

Both are effectors of the JAK/STAT pathway, known to act differently in male and female gonads (Decotto and Spradling 2005).

The hedgehog signaling pathway appears to act upstream of Wnt/β-catenin signaling during bone development and aberrant hedgehog signaling has been associated with cancer development and progression [ 58].