Sentence examples for pathways this study from inspiring English sources

In order to explore the potential mechanism(s) involved in the over-activation of direct striatal pathways, this study was designed to examine changes in prodynorphin (PDyn) gene expression as well as phosphorylation of dopamine and 32 kDa cAMP-regulated phosphoprotein (DARPP-32) in rats with LID using in situ hybridization and immunoblotting.

For the Myc, c-Src, HER2, EGFR, cyclin D1, Akt, and androgen pathways, this study provides the set of genes relevant to each pathway both experimentally and pathologically (Table 3 and Supplementary Data File S3).

The explanatory pathways this study created may be plausible but they also suggest that the more complex the logical equations and their underlying constructs (here, policy goals), the more difficult they will be to empirically validate.

Since the expression of TNF-α and other inflammatory mediators such as cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) is regulated by the NF-κB and activator protein (AP -1 pAP -1ys, this study was intended to analyze the effect of moderate hypathwaysa during CPB on thise studyling pathwass intendedyocardium.

Future work will clearly be necessary to determine why the p11 light chain seems dispensable for AnxA2 functions in the degradation pathway (this study), while the (AnxA2 2- p11 2 heterotetramer plays a role in the subcellular distribution of early and recycling endosomes [11], [12].

Regardless of the causal pathway, this study shows the importance of targeting low SES youth in intervention programs to enhance health behaviors.

And while rapamycin and dietary restriction both impact the mTOR pathway, this study demonstrated distinct difference in some metabolic parameters between rapamycin and dietary restriction, such as in the effect on leptin and FGF‐21 levels (Miller et al., 2014).

In addition to furthering our understanding of the sulfide oxidation pathway, this study also provides insight into two new metabolic activities previously unknown in animals, cysteine synthase and cyanoalanine synthase.

Owing to the importance of the EBF class of genes as key controllers of the ethylene signal transduction pathway, this study used the apple genome sequence to identify EBF-like genes.

* Transcription and translation related pathways # DNA repair related pathways In this study, we found that the bidirectional gene pairs were prevalent in eukaryotes and the percentage of bidirectional genes declines along with the increasing of genome size.

In the set of top 15 GeneGO pathways in our previous work, 11 (73.3%) were also detected in the 99 pathways in this study (see Additional file 5).