Sentence examples for pathways the primary from inspiring English sources

Much of the molecular signaling mediated by ERα involves the MAPK and phosphoinositide 3-kinase (PI3K) pathways, the primary facilitators of cell growth and proliferation [ 10].

The piRNA pathway itself is proposed to consist of two pathways, the primary piRNA pathway and the amplification or ping-pong pathway, the later acting in germ line tissues [ 31, 32].

For centrifugation-based pathways the primary energy required for natural gas drying is approximately 87% of total produced bioenergy, with corresponding life cycle GHG emissions of 44.62 g CO2 eq./MJ-biomass.

Edoxaban is a novel, oral anticoagulant that inhibits factor Xa (FXa), which is located at the confluence of the intrinsic and extrinsic coagulation pathways, the primary site of amplification in the coagulation cascade [ 1].

Activation of PKD can occur by multiple pathways, the primary one being non-classical PKC-dependent activation [ 5, 6] resulting from phosphorylation at serine residues within the catalytic domain (Ser/Ser in mouse PKD1, equivalent to Ser/Ser in human PKD1) [ 7], which occurs at the cell membrane following recruitment of both PKD and PKC by DAG.

In my graduate study working with Richard K. Bruick in Department of Biochemistry at UTSW, I characterized the function of ING4 protein in regulation of mammalian Hypoxia Response Pathway, the primary cellular response mechanism for oxygen deprivation.

Anti-angiogenic therapy via the VEGF pathway, the primary angiogenic pathway of macrophages, is ineffective, as tumor cells are able to activate other pro-angiogenic pathways [36].

Considering the ERK1/2 pathway, the primary input activator is activated Ras, a small GTPase.

In keeping with the dual-process theory we refer to the stimulus that induces learning as the primary stimulus and the corresponding stimulus-response pathway the primary pathway.

Citrate synthase is a component of the glyoxylate pathway, the primary route by which acetate is assimilated in E. coli.

In the majority of cases (81%) increased AKT signalling overlapped with recovery of signalling in the MAPK pathway, with the AKT pathway representing the primary resistance pathway in only a minority of cases (Shi et al, 2014).