Sentence examples for pathways that when from inspiring English sources
For example, many could indirectly affect cyst development by affecting metabolic pathways that when altered lead to induction of encystment.
The vision is anchored to the development of a suite of high-throughput assays for "toxicity pathways," which are normal biological signaling pathways that when sufficiently perturbed can lead to adverse effects in humans.
The vision of a National Research Council NRCcommitteethe (the Committee on Toxicity Testing and Assessment of Environmental Agents) for future toxicity testing involves the testing of human cells in in vitro assays for "toxicity pathways"—normal signaling pathways that when perturbed can lead to adverse effects.
We provide evidence for new cellular pathways that, when perturbed, selectively induce the apoptosis of mitotic arrested cancer cells, identifying a potential new strategy to enhance the therapeutic efficacy of conventional microtubule-targeting anti-cancer drugs.
These data have uncovered potential candidate genes and pathways that when perturbed lead to the development of the metabolic syndrome in older animals and therefore provide a focus for more detailed gene-specific studies.
RNAi screens performed herein were validated by identification of genes in pathways that, when previously targeted, enhanced paclitaxel sensitivity in the pre-clinical and clinical settings.
The BRAF protein is an important part of the MAPK molecular pathway that when constantly activated in this mutated state carries growth stimuli that promote carcinogenesis [ 9].
The basic idea is that a sleeping brain reactivates the same neural pathways that were activated when the memory was first formed.
For example, rafts may contain incomplete signaling pathways that are activated when a receptor or other required molecule is recruited into the raft.
In both cases, the cells greatly increase the range of C catabolic pathways that are active when serum is present.
Genetic screens in simple model organisms have identified many of the key components of the conserved signal transduction pathways that are oncogenic when misregulated.
