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However, the particular pathways that should be targeted to optimize therapeutic responses are unclear.
To keep the immune response under control, hosts have evolved regulatory pathways that should be considered when studying the target of the selection pressures acting on immunity.
Furthermore, the analysis of pathway mentions could provide valuable hints on pathways that should be prioritised for curation.
Transcriptome-based studies have provided molecular markers to identify possible pathways that should be inhibited in order to increase the efficacy of radiation treatment (Marston et al. 2009).
Importantly, we present several novel candidate genes and biochemical pathways that should be examined in future experiments for their role in hypoxia adaptation and fungal pathogenesis.
In the view of neuroinflammation-driven AD pathology, there are numerous attempts to identify the signaling pathways that should be blocked in order to obtain effective therapeutic intervention.
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In some instances the term is used at a conceptual level, to designate a pathway that should be there if the behavior is to be performed.
This study extends this approach; by identifying the preferred pathway that should be selected from the range of possible developed pathways.
Albeit this approach provides an overview of the different available options, it does not help to choose the best pathway that should be followed in current time to deal with uncertainty.
Another pathway, Wnt signaling, which is highly involved in development and adipogenesis could be another key pathway that should be investigated in LPS.
The results of our study can be used as part of a sophisticated but simple clinical pathway that should be implemented by a PCP that performs TJA.
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