Sentence examples for pathways that mediates from inspiring English sources

Some of the CMs induce autophagy via several signaling pathways that mediates the downregulation of mammalian target of rapamycin (mTOR) and upregulation of Beclin-1 [ 4, 5, 12].

It has been described as a scaffold protein in signaling pathways that mediates lysosomal degradation of activated FGF (fibroblast growth factor) receptors and subsequent attenuation of FGF signaling via its interaction with SPRED2 (sprouty-related, EVH1 domain containing 2).

So it's key to study not only him but other people, and to begin to answer some of these mysteries, such as whether you can reawaken dormant nerve pathways that mediate sensation or muscle function.

The adult cortex is organized into functionally distinct visual object-processing pathways that mediate this ability.

A future challenge will be to dissect the complex, interacting pathways that mediate the regulation of gibberellin metabolism.

Approaches to building on this discovery to understand the circuits and pathways that mediate the pathophysiology of schizophrenia are discussed.

Its multiple ligands and diverse roles attest to the need for exquisite control over the signaling pathways that mediate its effects.

This chapter describes the signaling pathways that mediate these phosphorylation events, their effect on initiation factor activity, and their significance in the regulation of translation initiation.

As mechanisms of ALI pathophysiology have been elucidated with time, other important pathways that mediate the lung injury response have been identified including activation of coagulation, specifically by upregulation of TF on the lung epithelium [10, 15].

However, three kinases [p38 mitogen-activated protein kinase (MAPK), AMP-activated protein kinase (AMPK), and calmodulin-dependent protein kinase] are particularly relevant in the signaling pathways that mediate skeletal muscle adaptations to endurance-based training [75,76].

We have begun to identify the signaling pathways that mediate profilin-dependent cellular responses in VSMCs.