Sentence examples for pathways that increase from inspiring English sources

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The chapter then describes the anatomy of the contractile machinery of striated and smooth muscle and discusses the signaling pathways that increase the contractile force and rhythmicity of the heart and cause contraction of arterial smooth muscle.

MHC class I transcription is regulated by two distinct types of regulatory pathways: 1) tissue-specific pathways that establish constitutive levels of expression within a given tissue and 2) dynamically modulated pathways that increase or decrease expression within that tissue in response to hormonal or cytokine mediated stimuli.

MHC class I expression is regulated by at least two distinct categories of pathways: 1) tissue-specific pathways that establish a baseline, or constitutive, level of transcription in any given tissue and 2) dynamically modulated pathways that increase or decrease expression in response to hormonal or cytokine mediated stimuli.

Lipid peroxidation products, such as MDA, can strongly activate redox-dependant pathways that increase inflammatory cytokine production and contribute to the exaggerated inflammatory responses in CF. Among lung peroxidases, Prdx6 has the unique ability to reduce PL-OOH, as other PL-OOH reductase enzymes have limited or no activity in this tissue [39] [39] [39].

Pathway enrichment analysis identified three major pathways that increase upon RO-3306 treatment.

This requires including pathways that increase risk (co-harms) or decrease it (co-benefits).

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It has been pointed out that one of the major pathways that increases ROS production in endothelial cells is the diacylglycerol (DAG)–protein-kinase C (PKC) pathway.

Though, 17 out of the top 20 pathways that increased between 2h and 4h of activation remained the same in the two age groups, we found that the 'NF-κB induced' pathway increased significantly only in the young group but not the old group.

Our transcriptome analysis captured multiple estrogen-responsive genes and signaling pathways that increased cell proliferation, promoted DNA damage and genome instability, and decreased tumor suppressing effects, suggesting a common mechanism for estrogen-induced carcinogenesis.

In conclusion, the three sets of co-expressed transcripts identified in response to VN1203-WT were associated with immune and apoptosis signaling pathways that increased over time, metabolic cellular processes that were largely decreasing, and T cell signaling pathways that exhibited a biphasic pattern.

They contract less forcefully and respond less strongly to the beta-adrenergic signaling pathway that increases heart rate and stroke volume and force in response to stress or exercise.

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