Sentence examples for pathways that function from inspiring English sources

Among conserved genes, we primarily selected M. loti genes of unknown function and those with regulatory functions, in order to reveal the biological roles of the functionally unannotated proteins and signal transduction pathways that function commonly among rhizobium species.

Recently, we have focused on defining the proteolytic pathways that function in the transition of breast cancer from the pre-invasive lesions of ductal carcinoma in situ (DCIS) to invasive ductal carcinomas (IDCs).

Mining this large expression dataset should assist in identifying associated components of these signaling pathways that function in orofacial formation.

By combining model simulations and experimental validations, we identified the essential components and pathways that function in our specific cell system.

There are other EGFR-downstream pathways that function in parallel to the MAPK pathway and which deserve our attention in future work.

Simulations with the model generated testable hypothesis on the response of the network upon perturbation, which were experimentally evaluated to identify the pathways that function in our particular liver cell system.

In order to acquire PPI information leads to understanding of signal transduction pathways that functioned in rhizobium, we screened M. loti genes with regulatory functions.

Among the signal pathways listed above, the DAG-PKC signal pathway is considered to be one of the most important intracellular transduction pathways that functions as a core effect in the onset and progression of diabetic cardiomyopathy.

The former was implemented through a de novo pathway that functions as an enzymatic reactor, while the latter was accomplished via synthetic circuits serving as genetic controllers.

Collectively, our results establish a GHS-R1a signaling pathway that functions to regulate PPARγ transcriptional potential in macrophages, which implicates ghrelin and GHS-R1a in the removal of cholesterol from vascular atherosclerotic lesions.

The phosphoinositide 3-kinase (PI3K) pathway is a key oncogenic signaling pathway that functions in cell survival and proliferation [ 22].