In contrast, polyplexes are internalized by unconventional endocytosis pathways that do not require dynamin or caveolin.
However, amygdalar lesions often do not impair appetitive learning, indicating that such learning is likely also supported by parallel neural pathways that do not involve the amygdala.
In addition to the classical clathrin-dependent mechanism of endocytosis, several pathways that do not use a clathrin coat are emerging.
Additionally, neurons and other cells in the brain are in constant communication through signaling pathways that do not act through synapses.
In addition to the classical clathrin-dependent mechanisms of endocytosis, there are several pathways that do not use a clathrin coat and are, therefore, referred to as clathrin-independent (CI) mechanisms.
β-arrestins also function as scaffolds for kinases and transduce signals from 7TMRs through pathways that do not require G protein activation.
We compare pathways from principal leadership through school organizational processes to student outcomes that include teacher influence as a mediating factor to pathways that do not include teachers' influence.
The vaccine, which is made by Merck, and a second one developed by GlaxoSmithKline that also has been tested during the recent Ebola epidemic in West Africa, may still come to market through alternative pathways that do not require as rigorous a level of proof that they work.
However, it likely signals through pathways that do not directly involve the GFRα1 receptor.
Albuminuria is a subclinical condition that may appear years before diagnosed CKD, and CKD may follow pathophysiological pathways that do not involve albuminuria.
Collectively, these data support that DNSP-11 exhibits potent neurotrophic actions analogous to GDNF, but likely signals through pathways that do not directly involve the GFRα1 receptor.
