Sentence examples for pathways that constitute from inspiring English sources

A system of regulatory molecules interacts at the cellular level to control and coordinate the many metabolic pathways that constitute normal mineral metabolism.

Therefore, studying the activity of multiple signaling pathways that constitute a proinflammatory signalome is essential for a better understanding of the pathogenesis of TRAPS.

An unbiased analysis of the gene expression datasets allowed us to identify the pathways that constitute the secondary response of an FdGOGAT1/GLU1 knock-down.

Our finding is only one point of the complicated cascades, and our finding does not exclude the involvements of any other molecules and/or pathways that constitute to the complex machinery.

Evidence supporting the first theme comes from the observation of shared Met/MET expression in the structures and axon pathways that constitute core limbic circuitry (Papez 1937; MacLean 1955).

For comparison with the projections of the adjacent TLCv and SC, it is noteworthy that TLCd projections are largely ascending and predominantly ipsilateral, and that TLCd axons do not contribute to the predorsal bundle or any of the descending pathways that constitute the main outflow of the intermediate and deep layers of the SC (see " Discussion").

Illustrations of gene interactions among DEG contained within the top two scoring networks can be seen in Figures  3 and 4. Biological pathways; lipid metabolism, cell growth and proliferation, and tissue development and function, were repeatedly featured pathways that constituted these top scoring networks.> Eighteen genes were validated by real-time RT-qPCR (Table  1).

EGFR and its ligands, the neuregulins initiate a signal transduction cascade involving the mitogen-activated protein kinase pathway that constitutes a growth stimulatory loop in lung cancer [7].

Research in the last years has unveiled an important role for neuroinflammation in the degeneration of the nigrostriatal dopaminergic pathway that constitutes the pathological basis of PD.

The pol β(E295K) mutation alters a critical residue in the sensor effector coupling pathway that constitutes the functional connection between correct base pair sensing and catalytic activation.

The downstream intracellular signaling pathways and transcription factors that constitute this complex program demonstrate significant crosstalk, including multiple positive feedback loops [ 46, 47].