Sentence examples for pathways that caused from inspiring English sources

Nevertheless, available studies using biopsy specimens from patients with Barrett's esophagus support a carcinogenetic role for alterations in the same pathways that caused transformation of our non-neoplastic Barrett's epithelial cells in vitro, i.e. the p16/Rb and p53 checkpoint arrest pathways, the mitogenic Ras signaling pathway, and the telomerase-dependent replicative senescence pathway.

To evaluate whether it was the block in selective autophagy pathways that caused the accumulation of ROS, or whether selective autophagy pathways are blocked as a consequence of increased ROS levels, we aimed to assess whether the inhibition of selective autophagy pathways caused by GABA could be suppressed by reducing ROS levels using glutathione.

The drug, sunitinib, is sold under the name Sutent and targets pathways that cause certain cancers to grow.

We then explicate the process pathways that cause soils to thicken and thin, and to even disappear, then reform.

A variation on the molecule targets the proteasomes in immune cells (which differ from those in normal cells), disrupting biochemical pathways that cause autoimmune disorders.

The increasing likelihood is that we're going to be able to discover, in a systematic way, the underlying molecular pathways that cause these diseases.

They also explored the exact signaling pathways that cause the problem, showing that the magnitude of signaling abnormalities could explain differences in symptom severity between family members.

With increasing knowledge of the molecular pathways that cause immunosenescence, therapeutic interventions can be designed to slow or halt the seemingly inevitable deterioration of protective immunity with aging.

The team will assess the chemical and physical properties that make particular molecules toxic, modeling the specific pathways that cause oxidative stress, a disruption in the normal redox state of cells.

The new technique, from Bio-X affiliate Jin Hyung Lee and Bio-X Fellow Andrew Weitz, probes the neural pathways that cause Parkinson's disease tremors, and also provides a way to map and troubleshoot other circuits in the whole brain.

Medicinal chemists at TDI whose contributions she calls "priceless"—are helping to develop compounds to block the molecular pathways that cause these vessels to leak, with the goal of establishing proof of concept in a mouse model.