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Attenuation of signaling pathways stimulated by pathologically activated FGF-receptor 2 mutants prevents craniosynostosis.
Our study finds multiple facets of the ATDC, i.e., the cleavage between the macro-level of policy design and micro level of implementation realities; the interplay between knowledge and politics, and appearance of possible alternative development pathways stimulated by ATDCs in African countries.
The signal transduction pathways stimulated by the mutants vis-à-vis the parent, as well as the cognate cytoskeletal changes that take place, remain to be investigated.
The mechanism of immunosuppression of HSP10 is less well defined but is believed to inhibit intracellular signaling pathways stimulated by ligand interaction with selected Toll-like receptors (TLRs) [17].
The ability of Tat to potentiate activation of signaling pathways stimulated by IFN-γ and TNF-α is an ingenious approach by the virus to exploit the activated cells into generating reservoirs of pro-inflammatory factors, such as CXCL10.
Matrix NO reduces oxygen uptake and ATP levels [17], thereby increasing the level of reduced equivalents and acetyl-S-coenzyme A (acetyl-CoA), the substrates for anaplerotic reactions and synthesis pathways stimulated by insulin.
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DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein.
Store-operated calcium channels (SOCs) are a nearly ubiquitous Ca(2+) entry pathway stimulated by numerous cell surface receptors via the reduction of Ca(2+) concentration in the ER.
By scanning election microscopy and zeta potential analysis, the proposed mechanism of Au@NP formation was that Shewanella used lactate as electron donors for the Mtr pathway, stimulated by photosensitive proteins resulting in the nucleation of NPs on the cell membrane.
We performed additional in vitro studies to visualize the postulated proinflammatory pathway stimulated by Ang-(1 7).
To explore the signal transduction pathway stimulated by PGN in monocytes and leading to TNFα production, we tested whether MAP kinases in monocytes were stimulated by PGN.
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