Sentence examples for pathways required to from inspiring English sources

The retention of genes for, and the involvement of many gene products in, VSG folding indicates a substantial complexity within the pathways required to perform this role.

Other genes isolated in the screen and that therefore have functions related to the cell response to caffeine might be indirectly affecting pathways required to counteract the effects of caffeine or required to facilitate its degradation.

Previous characterisation of the oncogenic pathways required to transform these cells showed that, as for other cell types, expression of SV40 Large T antigen (LT), which inactivates the p53 and Rb pathways, permits the cells to proliferate mitogen-independently but they retain a strict requirement for attachment and exhibit contact inhibition of proliferation.

These elements activate key pathways required to support replicative immortality and anchorage independent growth, a predictor of tumorigenesis in vivo.

Our data do not allow us to determine unambiguously the pathways required to generate the observed conversion tracts.

Our previous efforts to systematically catalog CIN phenotypes among essential yeast genes have uncovered the cellular pathways required to maintain genome stability (Stirling et al. 2011).

"In order for insects to have legs and still walk around, they have to retain at least a portion of that pathway required to make a wing," he says.

Thus, extensive experimentation is required to determine the chaperone pathway required to fold a specific protein.

Given the widespread nature of LPMOs, it is likely that N. crassa consumes aldonic acids, although the pathway required to do so remains unknown.

This metabolic pathway can be subdivided into two parts: an upstream sub-pathway required for achieving proper folding for most of the proteins synthesized in the secretory pathway, and a downstream sub-pathway required to give variability to trans-membrane proteins, and involved in adaptation to the environment and innate immunity.

Preliminary direct tests performed in human cells suggested that members of a pathway required to remove reactive oxygen species (ROS) would be excellent candidates for further study and specifically focused our attention on superoxide dismutase 1 (SOD1).