Sentence examples for pathways reduce the from inspiring English sources

But could the modification of metabolic pathways reduce the inflammatory responses associated to classical inflammatory diseases?

Previously, we and others have shown that cAMP and cGMP signaling pathways reduce the release and activity of platelet ADP and TxA2 under both stirred and static conditions [16].

While configurational sampling along reaction coordinates may expose other pathways, reduce the free-energy barrier, and bring the computed values into better agreement with experiment, the reason for the discrepancy remains an open question.

BR signaling pathways reduced the stomata density by suppressing the BIN2 triggered inactivation of YDA-mediated stomata development signaling cascades (Kim et al. 2012), indicating that higher BR activity could decrease water loss under drought and salt stress conditions.

And, conversely, the down-regulation of prostaglandin pathways reduces the constraints that would normally act to attenuate these proinflammatory pathways.

Inhibitors of the JNK and NF-κB pathways reduced the TNFα-stimulated expression of mPGES-1 and to a higher extent COX-2, accompanied by abolished PGE2 production.

Inhibition of these TNFα-activated signal pathways reduced the expression of mPGES-1 and COX-2 as well as their end product PGE2 in gingival fibroblasts.

Elementary flux modes are thermodynamically and stoichiometrically possible pathways reducing the complex metabolism into all, unique, non-decomposable biochemical pathways [ 24], which connect the supplied substrates with the corresponding end products.

Together, these data showed that the combined inhibition of EMT and apopototic pathways reduces the ability of multiple, but not all, differentiation-inducing miRNAs to silence the self-renewal of ESCs.

Our findings indicate that defects in the endocytic or recycling pathway reduce the toxicity triggered by the Aβ-GFP chimeric proteins.

In this study, we found that UDCA regulated metabolic pathways (mainly the phenylalanine/tyrosine pathway), reduced the miR-122 expression level, remodelled the microbiome, and changed the bile acid content, thus exerting protective effects on liver function.