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Constitutive activation of Ras pathways plays a critical role in cancer development and maintenance.
The imbalance between proinflammatory and anti-inflammatory pathways plays a role in polycystic ovary syndrome (PCOS) etiology.
Adenosine tri-phosphate (ATP), the most important energy source for metabolic reactions and pathways, plays a vital role in the growth of industrial strain and the production of target metabolites.
Indeed, dissecting TLR downstream signaling pathways plays a fundamental role in exploring novel therapeutic strategies based on the concept that hepatic I/R injury represents a case for host "innate" immunity.
We have shown that apoptotic cell death mediated through mitochondrial and caspase pathways plays a critical role in disease progression in HSPB5 R120G cardiomyopathy [18].
Because the fidelity of endocytic transport from internalization to lysosome delivery and proper coupling to signaling pathways plays a pivotal role in the maintenance of myelination and axonal function of sensory and motor neurons it becomes important to understand the mechanistic details of how the disease specific mutations alter intracellular signaling.
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Wnt signaling pathways play a critical role in lung development.
Signal transduction pathways play a key role in many cellular functions as well as intercellular communication.
Inflammatory pathways play a crucial role in the pathomechanisms of antidepressant efficacy.
Over activation of signaling pathways play a major role in oncogenesis.
Dopaminergic pathways play a key role in the central control of sexual behavior.
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CEO of Professional Science Editing for Scientists @ prosciediting.com