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These process-induced compounds, formed by close reaction pathways, play an important role as markers of food safety and quality.
Notch receptor signaling pathways play an important role, not only in normal breast development but also in breast cancer development and progression.
Because epigenetic pathways play an important role in regulation of fibrosing processes, we evaluated patient scars for DNA hydroxymethylation (5-hydroxymethylcytosine; 5-hmC) status and documented a significant decrease in scar fibroblasts.
Both reaction pathways play an important role in the kinetics of CH4 oxidation as CH3 + HO2 → CH3O + OH is a chain-branching reaction whereas CH3 + HO2 → CH4 + O2 a chain termination reaction.
These findings suggest that cell stress signaling pathways play an important role in γ-globin gene induction and may provide novel targets for the pharmacologic induction of fetal hemoglobin.
Notch signaling and its crosstalk with many signaling pathways play an important role in breast cancer cell growth, migration, invasion, metastasis and angiogenesis, as well as cancer stem cell (CSC) self-renewal.
These studies suggest that estrogen initiates mitogenesis by inducing the transcription of immediate early genes, but cytoplasmic signaling pathways play an important role in the control of subsequent events in the cell cycle.
Several lines of evidence suggest that DNA repair pathways play an important role in ovarian carcinogenesis.
Both the MAP kinase and PI3K/Akt pathways play an important role in the pathogenesis of melanoma.
These results indicate that both FASN and AKT pathways play an important role in p63-mediated cell survival.
Degradative pathways play an important role in signal termination, antigen presentation, and digestion of unnecessary materials by lysosomal degradation [1], [2].
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