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Studies on sleep and locomotor activity in mice [22], [33] and rats [34] with SCN lesions have used animals that were behaviorally arrhythmic in LD, suggesting that pathways required for the suppression of activity ("masking") by light were interrupted, either through collateral damage from the lesions or because these pathways pass through the SCN.
Inhibition of the parasympathetic nervous system arises from the frontal cortex, and the pathways pass through the amygdala and then to the nucleus tractus solitarii and nucleus ambiguus.
Terms in several small pathways' pass the threshold distance of 11.2, indicating that small pathways can contain semantically diverse enriched terms, which if omitted from the functional profile, could result in useful information being lost.
The high in-/out-degree indicates that TS TFs tend to regulate a large number of targets, and that TS TFs are regulated by a large number of regulators, while the high betweenness values show that TS TFs locate to bridge positions through which many regulatory pathways pass.
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The chosen pathways passing the criteria on filter are color coded according to users' preferences.
Different trafficking pathways passing through the endosomes are coordinated by the ENTH/ANTH/VHS adaptor protein superfamily.
Note, for the sake of interpretation, 175 pathways passed our gene pathway size filter criteria (min = 15 probes; max = 250 probes).
The probability of a signal to pass through the link of node i and j is then proportional to the number of pathways passing through this link.
Note that for each method, we selected the pathways passing either tier one or tier two criterion so that all detected pathways were included.
We also have relatively little understanding of the molecular pathways passing between the malignant cells and the stromal cells that these agents perturb.
Wyburn-Mason syndresultssults from a defect occurring during embryonic development of the vascular mesoderm, related to the visual pathways passing from the retina to the mesencephalon [ 3].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com