Sentence examples for pathways or large from inspiring English sources

Our study clearly illustrated a rational way to narrow down the genes of MR candidates, and is fundamentally different from metaphysical presentations, such as biological pathways or large network forms.

Therefore, our favored hypothesis is that the granules facilitate coordinated protein production, maybe allowing a precise stoichiometric balance in protein levels across specific pathways or within large multimeric complexes.

Can such invariant quantities be exploited to understand strategies for the regulation of whole pathways or even larger modules?

These genes are involved in cell division, translational initiation and acetyl-CoA carboxylase pathways, or photosystem I, large ribosomal subunits.

More importantly, our weighted integrative network is constructed to take into consideration possible features of genes in the driver pathways or core modules: large coverage, mutual exclusivity, strong influence of a gene's mutation on other genes, and high correlation of gene mutation-correlated expressions.

Large pathways or pathways with genes that reside in large LD blocks are likely to inflate the pathway statistic, although we accounted partially for this potential bias via the permutations procedure.

One possible developmental strategy for biased ligands would rely upon identifying a compound with a much higher affinity for one of the signaling pathways (very large or small ε in Figure 2C) rather than concentrating solely on differences in efficacy that result from transducer ratios.

Such approaches allow interpretation of significant genes in the setting of their pathway interactions and functional relevance; however, they are limited in their ability to search for significantly expressed genes that form a small component of large pathways or interact across multiple gene sets.

However, it is well known that proteins function as part of larger pathways or macromolecular structures and it is through these combined functions that selection actually acts (see [ 1]).

Previous research on this question has relied on coarse anatomy (mapping large fiber pathways) or functional connectivity (mapping inter-regional statistical dependencies in ongoing activity).

Biochemical pathways or networks are typically very large.