Sentence examples for pathways of target from inspiring English sources

Apart from kinase inhibitors with 'off-targets' activities, downstream signaling pathways of target kinases may also be involved in the development of toxicities.

In the field of drug residue analysis, knowledge of the main metabolic pathways of target analytes improves the efficiency of the corresponding control.

Failure of current chemotherapeutic agents to effectively treat human brain tumors has prompted the search for alternative regimens based on the inherent metabolic pathways of target cells.

Considering the nature of the action of pore forming toxins on mammalian cell membranes, we anticipated that mere binding, without pore formation, should not result in either cell death or substantial changes in the signaling pathways of target cells except initiating steps for repairing the membrane damage, if any.

KEGG pathways of target genes for downregulated miRNAs in gastric cancer.

A total of 53 most enriched pathways of target gene annotated in this study.

The Gene Ontology (GO) terms and KEGG pathways of targeted genes were annotated using the DAVID gene annotation tool (http://david.abcc.ncifcrf.gov/UTH).abcc.ncifcrf.gov/UTH

Tools added in the web interface also allow to inspect predictions according to gene ontology classes and metabolic pathways of targets.

Signaling pathway of target genes by KEGG database.

Although the mechanisms of target cell recognitions are different, NK cells and CTLs share the granule exocytosis pathway of target cell killing [ 66, 67].

Ricin, along with several protein toxins have been exploited for their intracellular trafficking and/or membrane translocation properties allowing delivery of exogenous peptides directly into the MHC class I processing and presentation pathway of target cells (1- 4).